a literature review on the efficacy and safety of botulinum toxin: an injection in post‑stroke spasticity
نویسندگان
چکیده
background: a variety of techniques for the management of spasticity have been suggested, including positioning, cryotherapy, splinting and casting, biofeedback, electrical stimulation, and medical management by pharmacological agents, botulinum toxin a (bta) is now the pharmacological treatment of choice in focal spasticity. bta by blocking acetylcholine release at neuromuscular junctions accounts for its therapeutic action to relieve spasticity. methods: a computerized search of pub med was carried out to find the latest result about efficacy of bta in management of post stroke spasticity. result: among 84 articles were found, frothy of them included in this review and divided to lower and upper extremity. conclusions: bta is a treatment choice in reducing tone and managing post stroke spasticity .
منابع مشابه
Botulinum toxin in poststroke spasticity.
Poststroke hemiparesis, together with abnormal muscle tone, is a major cause of morbidity and disability. Although most hemiparetic patients are able to reach different ambulatory levels with rehabilitation efforts, upper and lower limb spasticity can impede activities of daily living, personal hygiene, ambulation and, in some cases, functional improvement. The goals of spasticity management in...
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Background & Aims: The goal of this study was to determine the effect of foot serial casting along with botulinum toxin type-A injection on spasticity in children with cerebral palsy. Methods: This study was a randomized clinical trial performed as a pre-post, double blind study. It was performed on 25 children with hemiplegia and diplegia (2-8 years) in Tehran city, who were referred to valias...
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BACKGROUND AND OBJECTIVE Investigations were performed to establish if repetitive arm cycling training enhances the antispastic effect of intramuscular botulinum toxin (BTX) injections in postischemic spastic hemiparesis. Effects on cerebral activation were evaluated by functional magnetic resonance imaging (fMRI). METHODS Eight chronic spastic hemisyndrome patients (49 ± 10 years) after midd...
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The clinical eVects of botulinum toxin have been recognised since the end of the 19th century. It is the most potent neurotoxin known and it is produced by the gram negative anaerobic bacterium Clostridium botulinum. The paralytic eVect of the toxin is due to blockade of neuromuscular transmission. Injection into a muscle causes chemodenervation and local paralysis and this eVect has led to the...
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عنوان ژورنال:
international journal of preventive medicineجلد ۴، شماره ۱، صفحات ۱۴۷-۰
کلمات کلیدی
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